Hydrocortisone

Tocris Bioscience | Catalog # 4093

Adrenal glucocorticoid; immunosuppressant
Tocris Bioscience

Key Product Details

Description

Adrenal glucocorticoid; immunosuppressant
View all Glucocorticoid Receptor Compounds »

Product Description

Hydrocortisone is an adrenal glucocorticoid released in the stress response. Increases glucose production by gluconeogenesis. Immunosuppressant and antidiuretic hormone. Used in protocols to generate retinal pigment epithelial (RPE) cells from PSCs.

Product Specifications for Hydrocortisone

Molecular Weight

362.46

Formula

C21H30O5

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

11β,17α,21-Trihydroxypregn-4-ene-3,20-dione

CAS Number

50-23-7

PubChem ID

5754

InChI Key

JYGXADMDTFJGBT-VWUMJDOOSA-N

SMILES

O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@@]([H])2[C@@H](O)C[C@@]4(C)[C@]([H])3CC[C@@](O)4[C@@](CO)=O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 36.25 100
Ethanol 9.06 25

Preparing Stock Solutions for Hydrocortisone

The following data is based on the product molecular weight 362.46.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.76 mL 13.79 mL 27.59 mL
5 mM 0.55 mL 2.76 mL 5.52 mL
10 mM 0.28 mL 1.38 mL 2.76 mL
50 mM 0.06 mL 0.28 mL 0.55 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 36 publications citing the usage of this product.

Product Documents for Hydrocortisone

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Hydrocortisone

For research use only

Customer Reviews for Hydrocortisone (1)

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  • cell culture
    Name: Irving Garcia
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: ES cells
    Verified Customer | Posted 11/19/2020
    Used before always use from Tocris. Always works well in cell culture.

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