iFSP1
Tocris Bioscience | Catalog # 7162
Key Product Details
Description
Product Description
iFSP1 is a ferroptosis inducer. Inhibits ferroptosis suppressor protein 1 (FSP1) and induces ferroptosis in GPX4 knockout cells. Sensitizes tumor cells to RSL3 (Cat. No. 6118) -induced ferroptosis.
Product Specifications for iFSP1
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 6.47 | 20 |
Preparing Stock Solutions for iFSP1
The following data is based on the product molecular weight 323.36.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.2 mM | 15.46 mL | 77.31 mL | 154.63 mL |
| 1 mM | 3.09 mL | 15.46 mL | 30.93 mL |
| 2 mM | 1.55 mL | 7.73 mL | 15.46 mL |
| 10 mM | 0.31 mL | 1.55 mL | 3.09 mL |
Calculators
Background References
References are publications that support the biological activity of the product.
- Bersuker The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis. Nature 2019 PMID: 31634900
Product Documents for iFSP1
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for iFSP1
For research use only
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