Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Monoclonal Rat IgG1 Clone # 227702
View all IL-20R alpha Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse IL‑20 R alpha
Val33-Lys253
Accession # Q6PHB0

Specificity

Detect mouse IL-20 R alpha in direct ELISAs and Western blots. In direct ELISAs, this antibody does not cross-react with recombinant mouse IFN‑ alpha / beta  R1, recombinant human (rh) IFN-gamma R1, rhIFN-gamma R2, rhIL-10 R beta, rhIL-20 R alpha, or rhIL-20 R beta.

Clonality

Monoclonal

Host

Rat

Isotype

IgG1

Applications for IL-20R alpha Antibody (227702) [PE]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: IL-20R alpha

Official Gene Symbol: IL20RA Gene ID: 53832 (Human) Gene Map Locus: 6q22.33-q23.1 (Human) IL20RA, is a subunit of IL20R, a member of Cytokine Class II receptor super family. It consists of a central transmembrane domain and functionally induces IL20 and IL26 signaling in epithelial cells and keratinocytes. It associates with IL-20RB and forms a functional receptor complex for IL20, IL19, and IL24. It also associates with IL-10RB and forms a unique heterodimeric functional receptor complex for IL-26. Upon ligand binding, it induces signaling through activation of STAT3 and STAT1. IL20RA is specifically expressed in skin suggesting a prominent role in growth and proliferation of keratinocytes.

Long Name

Interleukin 20 Receptor alpha

Alternate Names

CRF2-8, IL-20 R alpha, IL-20R1, IL-20Ra, IL20R alpha, IL20RA, zcytor7

Gene Symbol

Il22ra2

Additional IL-20R alpha Products

Product Documents for IL-20R alpha Antibody (227702) [PE]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for IL-20R alpha Antibody (227702) [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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