IL-27 Antibody (B-G49)

Novus Biologicals | Catalog # NBP3-18128

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

ELISA Detection (Matched Antibody Pair)

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # B-G49
View all IL-27 Primary Antibodies »

Product Specifications

Immunogen

Recombinant IL-27. Hybridoma: Myeloma X63/AG.8653 x Balb/c node cells

Specificity

Recognizes both natural and recombinant IL-27

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Applications for IL-27 Antibody (B-G49)

Application
Recommended Usage

ELISA Detection (Matched Antibody Pair)

0.05-0.5ug/ml
Application Notes
The suggested coating concentration range below should be optimised by each laboratory for each application. This ELISA detection antibody paired with the ELISA capture antibody (NBP3-18127) is used for highly specific and sensitive detection of IL-27.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS. With 1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: IL-27

IL27 is encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Long Name

Interleukin 27

Alternate Names

IL27

Gene Symbol

IL27

Additional IL-27 Products

Product Documents for IL-27 Antibody (B-G49)

Certificate of Analysis

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Product Specific Notices for IL-27 Antibody (B-G49)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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Associated Pathways

Th1 Differentiation Pathway Th1 Differentiation Pathway Thumbnail