IL-31 Antibody (MT313) - Azide and BSA Free

Novus Biologicals | Catalog # NBP3-18293

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Neutralization

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # MT313

Format

Azide and BSA Free
View all IL-31 Primary Antibodies »

Product Specifications

Immunogen

Recombinant human IL-31

Specificity

Native and recombinant human IL-31

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

Novus Biologicals Mouse IL-31 Antibody (MT313) - Azide and BSA Free (NBP3-18293) is a monoclonal antibody validated for use in Neutralization. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for IL-31 Antibody (MT313) - Azide and BSA Free

Neutralization: IL-31 Antibody (MT313) [NBP3-18293]

Neutralization: IL-31 Antibody (MT313) [NBP3-18293]

Neutralization: IL-31 Antibody (MT313) [NBP3-18293] - Neutralization of human IL-31 induced IL-6 production (see graph). To determine the neutralizing capacity and ND50, mixtures of human recombinant IL-31 (50 ng/ml) and various concentrations of NBP3-18293 were added to human aortic endothelial cells that had been pre-stimulated with recombinant human IFN-gamma (10 ng/ml). Following overnight incubation, cell supernatants were quantified in IL-6 ELISA.

Applications for IL-31 Antibody (MT313) - Azide and BSA Free

Application
Recommended Usage

Neutralization

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

0.2 um filtered PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-31

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting ofIL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma(Dillon et al., 2004 (PubMed 15184896)).(supplied by OMIM)

Long Name

Interleukin 31

Alternate Names

IL31

Gene Symbol

IL31

Additional IL-31 Products

Product Documents for IL-31 Antibody (MT313) - Azide and BSA Free

Certificate of Analysis

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Product Specific Notices for IL-31 Antibody (MT313) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

IL-6 Family

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FAQs

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Associated Pathways

Th2 Differentiation Pathway Th2 Differentiation Pathway Thumbnail