Iloprost

Tocris Bioscience | Catalog # 2038

Prostacyclin (PGI2) analog
Tocris Bioscience
Discontinued Product
2038 has been discontinued. View all Prostanoid Receptor Agonists products.

Key Product Details

Description

Prostacyclin (PGI2) analog

Alternative Names

ZK 36374
View all Prostanoid Receptor Agonists »

Product Description

Iloprost is a prostacyclin (PGI2) analog that binds with high affinity to IP, EP1 and EP3 receptors (Ki values are 11, 11, 56, 284, 619, 1035, 1870 and 6487 nM for IP, EP1, EP3, EP4, FP, DP, EP2 and TP receptors respectively). Inhibits platelet aggregation induced by collagen, thrombin and ADP (IC50 values are 0.24, 0.71 and 1.07 nM respectively).

Product Specifications for Iloprost

Molecular Weight

360.49

Formula

C22H32O4

Storage

Store at -20°C

Purity

≥97% (HPLC)

Chemical Name

(5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-ynyl]-2(1H)-pentalenylidene]pentanoic acid

CAS Number

78919-13-8

PubChem ID

5311181

InChI Key

HIFJCPQKFCZDDL-ACWOEMLNSA-N

SMILES

O[C@@H]1C[C@H]2[C@H](C/C(C2)=C/CCCC(O)=O)[C@H]1/C=C/[C@@H](O)C(C)CC#CC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble in methyl acetate (supplied pre-dissolved - 5mg/ml)

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 19 publications citing the usage of this product.

Product Documents for Iloprost

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Iloprost

For research use only

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