Recombinant Human INCA His Protein

Name: Recombinant Human INCA His Protein
Brand: Novus Biologicals
SKU: NBP2-22737
Price: 329 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-22737

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE

View all INCA Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-110 of Human INCA

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMADKVLK EKRKQFIRSV GEGTINGLLG ELLETRVLSQ EEIEIVKCEN ATVMDKARAL LDSVIRKGAP ACQICITYIC EEDSHLAGTL GLSAGPTSGN HLTTQDSQIV LPS

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

14.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human INCA His Protein

SDS-PAGE: Recombinant Human INCA His Protein [NBP2-22737]

SDS-Page: Recombinant Human INCA Protein [NBP2-22737]

Formulation, Preparation, and Storage

NBP2-22737

Formulation	20 mM Tris-HCl buffer (pH 8.0), 0.15 M NaCl, 20% glycerol, 1 mM DTT
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: INCA

CARD17 is a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. This protein inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, CARD17 do not induce NF-kappa-B activation. Recombinant human CARD17 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

caspase recruitment domain family, member 17, caspase recruitment domain-containing protein 17, Caspase-1 inhibitor INCA, INCAInhibitory CARD, inhibitory caspase recruitment domain (CARD) protein, Inhibitory caspase recruitment domain protein

Gene Symbol

CARD17P

Additional INCA Products

Product Documents for Recombinant Human INCA His Protein

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Product Specific Notices for Recombinant Human INCA His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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