Isoguvacine hydrochloride

Key Product Details

Product Description

Isoguvacine hydrochloride is a specific GABA_A receptor agonist. Suppresses low magnesium induced seizure like events in organotypic hippocampal brain slices.

Product Specifications for Isoguvacine hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Isoguvacine hydrochloride

The following data is based on the product molecular weight 163.60.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	6.11 mL	30.56 mL	61.12 mL
5 mM	1.22 mL	6.11 mL	12.22 mL
10 mM	0.61 mL	3.06 mL	6.11 mL
50 mM	0.12 mL	0.61 mL	1.22 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 12 publications citing the usage of this product.

• Krogsgaard-Larsen Dihydromuscimol, thiomuscimol and related heterocyclic compounds as GABA analogues. J.Neurochem. 1979 PMID: 448364
• Wahab Effects of gamma-aminobutyric acid (GABA) agonists and a GABA uptake inhibitor on pharmacoresistant seizure like events in organotypic hippocampal slice cultures. Epilepsy Res. 2009 PMID: 19535226
• Krogsgaard-Larsen Structure-activity studies on the inhibition of GABA binding to rat brain membranes by muscimol and related compounds. J.Neurochem. 1978 PMID: 670980

Product Documents for Isoguvacine hydrochloride