L-689,560

Key Product Details

Product Description

L-689,560 is a very potent antagonist at the glycine-NMDA site.

Licensing Information

Sold with the permission of Merck Sharp and Dohme Ltd.

Product Specifications for L-689,560

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for L-689,560

The following data is based on the product molecular weight 380.23.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

6 5 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.63 mL	13.15 mL	26.30 mL
5 mM	0.53 mL	2.63 mL	5.26 mL
10 mM	0.26 mL	1.31 mL	2.63 mL
50 mM	0.05 mL	0.26 mL	0.53 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 64 publications citing the usage of this product.

• Stone Development and therapeutic potential of kynurenic acid and kynurenine derivatives for neuroprotection. TiPS 2000 PMID: 10740291
• Leeson trans-2-Carboxy-4-substituted tetrahydroquinolines. Potent glycine-site NMDA receptor antagonists. Med.Chem.Res.
• Leeson 4-Amido-2-carboxytetrahydroquinolines. Structure-activity relationship for antagonism at the glycine site of the NMDA receptor. J.Med.Chem. 1992 PMID: 1534584

Product Documents for L-689,560