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L-DON

Catalog #: 6809 Datasheet / COA / SDS

Discontinued Product

6809 has been discontinued.
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L-DON | CAS No. 157-03-9 | Glutaminase Inhibitors
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Description: Glutaminase inhibitor; also inhibits other glutamine-using enzymes and transporters

Chemical Name: 6-Diazo-5-oxo-L-norleucine

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Biological Activity

L-DON is a glutaminase inhibitor (Ki = 6 μM). Also inhibits other glutamine-using enzymes, amino acid transporters and transglutaminases. Displays antitumor effects and reduces tumor weight in a range of mouse xenograft models.

Technical Data

M.Wt:
171.15
Formula:
C6H9N3O3
Solubility:
Soluble to 50 mM in water
Storage:
Store at -20°C
CAS No:
157-03-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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