L-Glutamic acid

Tocris Bioscience | Catalog # 0218

Endogenous, non-selective glutamate receptor agonist
Tocris Bioscience

Key Product Details

Description

Endogenous, non-selective glutamate receptor agonist
View all Non-selective mGluR Agonists »

Product Description

L-Glutamic acid is a the predominant excitatory transmitter in the mammalian central nervous system. L-Glutamic acid acts at ionotropic and metabotropic glutamate receptors.

MNI-caged-L-glutamate (Cat. No. 1490) also available.

Product Specifications for L-Glutamic acid

Molecular Weight

147.13

Formula

C5H9NO4

Storage

Store at RT

Chemical Name

(S)-1-Aminopropane-1,3-dicarboxylic acid

CAS Number

56-86-0

PubChem ID

33032

InChI Key

WHUUTDBJXJRKMK-VKHMYHEASA-N

SMILES

[H][C@@](CCC(O)=O)(N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
1eq. NaOH 100

Preparing Stock Solutions for L-Glutamic acid

The following data is based on the product molecular weight 147.13.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 6.80 mL 33.98 mL 67.97 mL
5 mM 1.36 mL 6.80 mL 13.59 mL
10 mM 0.68 mL 3.40 mL 6.80 mL
50 mM 0.14 mL 0.68 mL 1.36 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 91 publications citing the usage of this product.

Product Documents for L-Glutamic acid

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for L-Glutamic acid

For research use only

Citations for L-Glutamic acid

Customer Reviews for L-Glutamic acid (3)

4.7 out of 5
3 Customer Ratings
5 Stars
67%
4 Stars
33%
3 Stars
0%
2 Stars
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1 Stars
0%

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Showing  1 - 3 的 3 reviews Showing All
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  • Action of felbamate and beta-alanine on NMDA receptors
    Name: Anonymous
    Species: Mouse
    Assay Type: Ex Vivo
    Cell Line/Tissue: Cerebellum
    Verified Customer | Posted 06/21/2023
    Glutamic acid (10 mM) + glycine (10 mM) were used to activate NMDA receptors in outside-out membrane patch and then test action of beta-alanine and felbamate on glycine binding site. As expected, activation of NMDARs was fully legible.
    L-Glutamic acid 0218
  • Neuron glia culture
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: Mixed neuron-glia
    Verified Customer | Posted 07/12/2020
    Incubate for 24h
    L-glutamate (10 or 100μM)
    L-Glutamic acid 0218
  • works good
    Name: Anonymous
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: Sprague-Dawley rats primary neuronal
    Verified Customer | Posted 04/04/2020
    10 μM L-Glutamic acid for 2 hours
    L-Glutamic acid 0218

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