Lac-Phe

Key Product Details

Product Description

Lac-Phe is a metabolite generated from lactate and phenylalanine by cytosolic non-specific dipeptidase (CNDP2) during intense exercise. Lac-Phe reduces food intake in diet-induced obese mice without affecting movement or energy expenditure. When administrated chronically, Lac-Phe decreases adiposity and body weight and improves glucose homeostasis.

Product Specifications for Lac-Phe

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Lac-Phe

The following data is based on the product molecular weight 237.26.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.21 mL	21.07 mL	42.15 mL
5 mM	0.84 mL	4.21 mL	8.43 mL
10 mM	0.42 mL	2.11 mL	4.21 mL
50 mM	0.08 mL	0.42 mL	0.84 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Li An exercise-inducible metabolite that suppresses feeding and obesity. Nature 2022 PMID: 35705806

Product Documents for Lac-Phe