Lamotrigine isethionate
Tocris Bioscience | Catalog # 2289
Key Product Details
Description
Product Description
Lamotrigine isethionate is a water-soluble salt of lamotrigine (Cat. No. 1611). Displays anticonvulsant effects and inhibits glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents.
Licensing Information
Sold for research purposes under agreement from GlaxoSmithKline
Product Specifications for Lamotrigine isethionate
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 38.22 | 100 with gentle warming |
Preparing Stock Solutions for Lamotrigine isethionate
The following data is based on the product molecular weight 382.22.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.62 mL | 13.08 mL | 26.16 mL |
| 5 mM | 0.52 mL | 2.62 mL | 5.23 mL |
| 10 mM | 0.26 mL | 1.31 mL | 2.62 mL |
| 50 mM | 0.05 mL | 0.26 mL | 0.52 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 10 publications citing the usage of this product.
- Grunze Modulation of calcium and potassium currents by lamotr. Neuropsychobiology 1998 PMID: 9778600
- Smith and Meldrum Cardioprotective effect of lamotr. after focal ischemia in rats. Stroke 1995 PMID: 7839380
- Zona and Avoli Lamotrigine reduces voltage-gated sodium currents in rat central neurons in culture. Epilepsia 1997 PMID: 9184596
- Leach Neurochemical and behavioral aspects of lamotr. Epilepsia 1991 PMID: 1685439
Product Documents for Lamotrigine isethionate
Product Specific Notices for Lamotrigine isethionate
For research use only
Citations for Lamotrigine isethionate
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