LF 11

Name: LF 11
Brand: Tocris Bioscience
SKU: 4421

Catalog #: 4421 Datasheet / COA / SDS

Discontinued Product

4421 has been discontinued.

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Description: Antibiotic; neutralizes LPS

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Product Details

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Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

LF 11 is a peptide based on the lipopolysaccharide (LPS)-binding region of human lactoferricin. Neutralizes LPS; displays antimicrobial activity against Gram-negative and Gram-positive bacteria. Analog lauryl-LF 11 (Cat. No. 4422) available.

Technical Data

M.Wt:

1529.81

Formula:

C₆₉H₁₁₂N₂₆O₁₄

Sequence:

FQWQRNIRKVR

(Modifications: Arg-11 = C-terminal amide)

Solubility:

Soluble to 2 mg/ml in 20% acetonitrile / water

Storage:

Store at -20°C

CAS No:

832729-13-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide.
Andra et al.
Biochem.J., 2005;385:135
Comparative analysis of selected methods for the assessment of antimicrobial and membrane-permeabilizing activity: a case study for lactoferricin derived peptides.
Sanchez-Gomez et al.
BMC Mirobiol., 2008;11:196
Structural origin of endotoxin neutralization and antimicrobial activity of a lactoferrin-based peptide.
Japelj et al.
J.Biol.Chem., 2005;280:16955

Product Datasheets

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SDS

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M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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