Linezolid

Tocris Bioscience | Catalog # 3765

Antibiotic; inhibits protein synthesis in gram-positive bacteria
Tocris Bioscience
Discontinued Product
3765 has been discontinued. View all Antibiotics products.

Key Product Details

Description

Antibiotic; inhibits protein synthesis in gram-positive bacteria

Alternative Names

PNU 100766,U 100766
View all Antibiotics »

Product Description

Linezolid is an oxazolidinone antibiotic. Inhibits bacterial protein synthesis prior to chain initiation. Displays potent antibacterial activity against a variety of multidrug-resistant gram-positive microbes in vitro and in vivo. Identified as targeting human host cell proteins that interact with SARS-CoV-2.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Product Specifications for Linezolid

Molecular Weight

337.35

Formula

C16H20FN3O4

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

N-[[(5S)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-acetamide

CAS Number

165800-03-3

PubChem ID

441401

InChI Key

TYZROVQLWOKYKF-ZDUSSCGKSA-N

SMILES

FC1=CC(N3C[C@H](CNC(C)=O)OC3=O)=CC=C1N2CCOCC2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 33.74 100
Ethanol 8.43 25

Preparing Stock Solutions for Linezolid

The following data is based on the product molecular weight 337.35.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.96 mL 14.82 mL 29.64 mL
5 mM 0.59 mL 2.96 mL 5.93 mL
10 mM 0.30 mL 1.48 mL 2.96 mL
50 mM 0.06 mL 0.30 mL 0.59 mL

Calculators

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Product Documents for Linezolid

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Linezolid

For research use only

Customer Reviews for Linezolid (2)

4.5 out of 5
2 Customer Ratings
5 Stars
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4 Stars
50%
3 Stars
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2 Stars
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1 Stars
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  • Used Linezolid to identify its effectivenes against MRSA infections
    Name: Anonymous
    Species: Human
    Verified Customer | Posted 02/18/2019
    Used Linezolid to identify its effectivenes against MRSA infections caused by hospitalization.
    Linezolid 3765
  • Linezolid was used in resistance studies
    Name: Jade Smith
    Species: Human
    Verified Customer | Posted 02/05/2019
    Linezolid was used in resistance studies. Antibiotic susceptibility testing was done for each isolate by the Kirby-Bauer disc diffusion method (DDM). The antibiotic works ideally and would use again.
    Linezolid 3765

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