Lithium carbonate
Tocris Bioscience | Catalog # 4740
Key Product Details
Description
Product Description
Lithium carbonate is a mood stabilizer; thought to act by reducing catecholamine neurotransmitter concentration, through an effect on the Na+/K+ ATPase pump. Effective in the treatment of bipolar disorder. Inhibits GSK-3 in vivo.
Product Specifications for Lithium carbonate
Molecular Weight
Formula
Storage
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 7.39 | 100 |
Preparing Stock Solutions for Lithium carbonate
The following data is based on the product molecular weight 73.89.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 13.53 mL | 67.67 mL | 135.34 mL |
| 5 mM | 2.71 mL | 13.53 mL | 27.07 mL |
| 10 mM | 1.35 mL | 6.77 mL | 13.53 mL |
| 50 mM | 0.27 mL | 1.35 mL | 2.71 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.
- Gould In vivo evidence in the brain for Li inhibition of glycogen synthase kinase-3. Neuropsychopharmacology 2004 PMID: 12942141
- Lenox and Hahn Overview of the mechanism of action of Li in the brain: fifty-year update. J.Clin.Psychiatry 2000 PMID: 10826655
Product Documents for Lithium carbonate
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Lithium carbonate
For research use only
⚠ WARNING: This product can expose you to chemicals including Lithium carbonate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.govCitations for Lithium carbonate
Customer Reviews for Lithium carbonate (1)
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Species: Guinea PigAssay Type: In VitroCell Line/Tissue: Ventricular cardiomyocytesVerified Customer | Posted 10/23/2018Guinea pig ventricular cardiomyocytes were patched and stimulated at a 1 Hz frequency to record action potentials before and after Li2CO3 (10 and 30 µM). Li2CO3 significantly prolonged action potential duration at 20% and 90% repolarization levels.
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