LY 225910

Tocris Bioscience | Catalog # 1018

Potent CCK2 antagonist
Tocris Bioscience
Discontinued Product
1018 has been discontinued. View all CCK2 Receptor Antagonists products.

Key Product Details

Description

Potent CCK2 antagonist
View all CCK2 Receptor Antagonists »

Product Description

LY 225910 is a potent CCK2 receptor antagonist (IC50 = 9.3 nM for inhibition of 125I-labeled CCK-8 sulfate binding at mouse brain membranes).

Licensing Information

Sold with the permission of Eli Lilly and Company.

Product Specifications for LY 225910

Molecular Weight

502.41

Formula

C27H24BrN3O2

Storage

Desiccate at -20°C

Chemical Name

2-[2-(5-Bromo-1H-indol-3-yl)ethyl]-3-[3-(1-methylethoxy)phenyl]-4-(3H)-quinazoline

CAS Number

133040-77-4

PubChem ID

4355450

InChI Key

KUECXUACQOYKNB-UHFFFAOYSA-N

SMILES

CC(C)OC1=CC=CC(=C1)N1C(CCC2=CNC3=CC=C(Br)C=C23)=NC2=C(C=CC=C2)C1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 100

Preparing Stock Solutions for LY 225910

The following data is based on the product molecular weight 502.41.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.99 mL 9.95 mL 19.90 mL
5 mM 0.40 mL 1.99 mL 3.98 mL
10 mM 0.20 mL 1.00 mL 1.99 mL
50 mM 0.04 mL 0.20 mL 0.40 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 22 publications citing the usage of this product.

Product Documents for LY 225910

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for LY 225910

For research use only

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