m-3M3FBS

Key Product Details

Product Description

m

-3M3FBS is an activator of phospholipase C (PLC). Stimulates superoxide generation, Ca²⁺ release and inositol phosphate formation in a variety of cell types. Also inhibits growth of the leukemic cell lines U937 and THP-1.

Negative Control also available.

Product Specifications for m-3M3FBS

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for m-3M3FBS

The following data is based on the product molecular weight 343.36.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.91 mL	14.56 mL	29.12 mL
5 mM	0.58 mL	2.91 mL	5.82 mL
10 mM	0.29 mL	1.46 mL	2.91 mL
50 mM	0.06 mL	0.29 mL	0.58 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 50 publications citing the usage of this product.

• Krjukova Phospholipase C activator m-3M3FBS affects Ca²⁺ homeostasis independently of phospholipase C activation. Br.J.Pharmacol. 2004 PMID: 15302681
• Lee The novel phospholipase C activator, m-3M3FBS, induces monocytic leukemia cell apoptosis. Cancer Lett. 2005 PMID: 15863272
• Bae Identification of a compound that directly stimulates phospholipase C activity. Mol.Pharmacol. 2003 PMID: 12695532

Product Documents for m-3M3FBS