MG 624

Tocris Bioscience | Catalog # 1356

α7 neuronal nAChR antagonist
Tocris Bioscience
Discontinued Product
1356 has been discontinued. View all Nicotinic (a7) Receptor Antagonists products.

Key Product Details

Description

α7 neuronal nAChR antagonist
View all Nicotinic (a7) Receptor Antagonists »

Product Description

MG 624 is a selective antagonist for neuronal α7 subunit- containing nAChR subtypes. Inhibits α-Bgtx binding to chick α7 and α4β2 subtypes with Ki values of 106 nM and 84 μM respectively.

Product Specifications for MG 624

Molecular Weight

451.39

Formula

C22H30NOI

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

N,N,N-Triethyl-2-[4-(2-phenylethenyl)phenoxy]ethanaminium iodide

CAS Number

77257-42-2

PubChem ID

6433339

InChI Key

RDTKUZXIHMTSJO-UEIGIMKUSA-M

SMILES

[I-].CC[N+](CC)(CC)CCOC1=CC=C(\C=C\C2=CC=CC=C2)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 9.03 20
Ethanol 10

Preparing Stock Solutions for MG 624

The following data is based on the product molecular weight 451.39.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 11.08 mL 55.38 mL 110.77 mL
1 mM 2.22 mL 11.08 mL 22.15 mL
2 mM 1.11 mL 5.54 mL 11.08 mL
10 mM 0.22 mL 1.11 mL 2.22 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 8 publications citing the usage of this product.

Product Documents for MG 624

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for MG 624

For research use only

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  • The 5,760 bioactive compound library is a collated compound set of approved drugs and biologically active compound
    Name: Anonymous
    Species: C. albicans
    Assay Type: In Vitro
    Verified Customer | Posted 02/01/2020
    Biologically active compounds that have been documented to interact with a wide range of targets including SB-224289 (Cat. # 1221), MG-624 (Cat. # 1356), GVIA (Cat. No. 1085), DPAT hydrobromide (Cat. No. 1080) and valinomycin (VA; Cat. # 3373) were ordered from Tocris Bioscience
    MG 624 1356

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