MJ 15

Tocris Bioscience | Catalog # 4063

Potent and selective CB1 antagonist
Tocris Bioscience
Discontinued Product
4063 has been discontinued. View all Cannabinoid R1/CB1 Antagonists products.

Key Product Details

Description

Potent and selective CB1 antagonist

Product Description

MJ 15 is a potent and selective CB1 receptor antagonist (Ki = 27.2 pM, IC50 = 118.9 pM for rat CB1 receptors). Exhibits potency in obesity and hyperlipidemia models; inhibits food intake and increases in body weight in diet-induced obese rats and mice.

Licensing Information

Sold under licence.

Product Specifications for MJ 15

Molecular Weight

471.77

Formula

C23H17Cl3N4O

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(3-pyridinylmethyl)-1H-pyrazole-3-carboxamide

CAS Number

944154-76-1

PubChem ID

59377482

InChI Key

PJEIKJFNEFJFLA-UHFFFAOYSA-N

SMILES

ClC1=CC(Cl)=CC=C1N2C(C3=CC=C(Cl)C=C3)=C(C)C(C(NCC4=CC=CN=C4)=O)=N2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 47.18 100

Preparing Stock Solutions for MJ 15

The following data is based on the product molecular weight 471.77.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.12 mL 10.60 mL 21.20 mL
5 mM 0.42 mL 2.12 mL 4.24 mL
10 mM 0.21 mL 1.06 mL 2.12 mL
50 mM 0.04 mL 0.21 mL 0.42 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

Product Documents for MJ 15

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for MJ 15

For research use only

Related Research Areas

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