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MN 64

Catalog #: 5084 Datasheet / COA / SDS

Discontinued Product

5084 has been discontinued.
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MN 64 | CAS No. 92831-11-3 | Tankyrase Inhibitors
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Description: Potent and selective tankyrase inhibitor

Chemical Name: 2-[4-(1-Methylethyl)phenyl]-4H-1-benzopyran-4-one

Purity: ≥98%

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Biological Activity

Potent and selective tankyrase (TNKS) inhibitor (IC50 values are 6 and 72 nM for TNKS1 and TNKS2 respectively). Has no significant effect on PARP-1 or PARP-2 (IC50 >19 μM). Inhibits WNT/β-catenin signaling-dependent Super-TopFlash (STF) luciferase activity.

Technical Data

M.Wt:
264.32
Formula:
C18H16O2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
92831-11-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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