Mouse Activin RIIA (NP_031422) VersaClone cDNA

R&D Systems | Catalog # RDC2948

R&D Systems
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Key Product Details

Species

Mouse

Accession Number

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Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Activin RIIA

Activin RIIA (Activin Receptor IIA) is a transmembrane type II Ser/Thr kinase receptor that binds its ligands and then associates with type I receptors. Activin RIIA mediates the pleiotropic effects of Activins and Inhibins as well as several members of the BMP and GDF families of TGF-beta like proteins. Signaling through Activin RIIA is modulated by its interaction with RGM-B/DRAGON, Cripto, Endoglin/CD105, TGF-beta RIII/Betaglycan, or BAMBI. These interactions can enhance ligand-induced signaling or interfere with signaling by preventing Activin RIIA association with type I receptors.

Long Name

Activin Receptor IIA

Alternate Names

ActivinRIIA, ACVR2A, AVR2A

Entrez Gene IDs

92 (Human); 11480 (Mouse)

Gene Symbol

ACVR2A

UniProt

Additional Activin RIIA Products

Product Documents for Mouse Activin RIIA (NP_031422) VersaClone cDNA

Certificate of Analysis

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Product Specific Notices for Mouse Activin RIIA (NP_031422) VersaClone cDNA

For research use only

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