Key Product Details

Species Reactivity

Validated:

Mouse

Cited:

Mouse

Applications

Validated:

Western Blot, Immunoprecipitation

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all Complement Component C1rLP Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Complement Component C1rLP
Ser18-Asp456
Accession # AAP41417

Specificity

Detects mouse Complement Component C1rLP in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 40% cross‑reactivity with recombinant human (rh) C1rLP is observed and less than 1% cross‑reactivity with rhC1R and rhC1S is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Mouse Complement Component C1rLP Antibody

Application
Recommended Usage

Immunoprecipitation

25 µg/mL
Sample: Conditioned cell culture medium spiked with Recombinant Mouse Complement Component C1rLP, see our available Western blot detection antibodies

Western Blot

0.1 µg/mL
Sample: Recombinant Mouse Complement Component C1rLP

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Complement Component C1rLP

Mouse C1rLP, also CLSPa, is a 55 kDa, secreted, atypical glycoprotein member of the AGY group of servine proteases. It has protease activity for pro-haptoglobin, but accomplishes cleavage without a typical Asp in the catalytic site. In addition, it is proposed to block unwanted complement-mediated proteolysis. Mature C1rLP is 443 amino acids (aa) in length. It contains one CUB domain (aa 43‑165), a truncated CCP2 region (aa 167‑223) and a serine protease domain (aa 239‑482). There is a potential short form that utilizes an alternate start site at Met 27. Over aa 44‑456, mouse C1rLP is 78% and 90% aa identical to human and rat C1rLP, respectively.

Long Name

Complement C1r Subcomponent-like Protein

Alternate Names

C1RL, C1RL1, CLSPa

Entrez Gene IDs

51279 (Human); 232371 (Mouse)

Gene Symbol

C1RL

UniProt

AAP41417

Additional Complement Component C1rLP Products

Product Documents for Mouse Complement Component C1rLP Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Mouse Complement Component C1rLP Antibody

For research use only

Citations for Mouse Complement Component C1rLP Antibody

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