Mouse DCIR/CLEC4A Alexa Fluor® 532-conjugated Antibody

Catalog #: FAB2617X Datasheet / COA / SDS

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FAB2617X-100UG

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All DCIR/CLEC4A Antibodies

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Mouse DCIR/CLEC4A Alexa Fluor® 532-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse DCIR/CLEC4A in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) DCIR or recombinant mouse DCAR is observed.

Source

Monoclonal Rat IgG2a Clone # 320511

Purification

Protein A or G purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse DCIR/CLEC4A isoform 1
Gln70-Leu238
Accession # Q9QZ15

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 532 (Excitation= 534 nm, Emission= 553 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: DCIR/CLEC4A

DCIR (Dendritic Cell Immunoreceptor), also known as LLIR (Lectin-like Immunoreceptor), is a type II membrane protein belonging to the C-type lectin domain family and is designated CLEC4A (previously designated CLECSF6). Four transcript variants encoding distinct isoforms have been identified. DCIR contains one carbohydrate recognition domain in its C-terminal extracellular domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. Besides DC, DCIR is expressed on B cells, monocytes/macrophages and granulocytes.

Long Name

Dendritic Cell Immunoreceptor

Entrez Gene IDs

50856 (Human); 26888 (Mouse)

Alternate Names

CD367; CLEC4A; CLECSF6; CLECSF6C-type lectin superfamily member 6; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 6; C-type lectin domain family 4 member A; C-type lectin domain family 4, member A; DCIR; DCIRLLIR; DDB27; DDB27C-type lectin DDB27; Dendritic cell immunoreceptor; Lectin-like immunoreceptor; LLIR