Mouse Exostosin-like 2/EXTL2 Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB2536V Datasheet / COA / SDS

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FAB2536V-100UG

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Mouse Exostosin-like 2/EXTL2 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse Exostosin-like 2/EXTL2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse EXTL1, recombinant human (rh) Exostosin-like 2/EXTL2, or rhEXTL3 is observed.

Source

Monoclonal Rat IgG2a Clone # 339509

Purification

Protein A or G purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Exostosin-like 2/EXTL2
Asn43-Met330
Accession # Q9ES89

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Exostosin-like 2/EXTL2

Exostosin-like 2/EXTL2 is a type II Golgi membrane protein with a C-terminal lumenal region that contains the catalytic domain. It is a glycosyl transferase that is required for the biosynthesis of heparan sulfate. The amino acid sequence of the mouse EXTL2 is 93%, 90%, 87% and 81% identical to that of rat, canine, human and chicken.

Entrez Gene IDs

2135 (Human); 58193 (Mouse)

Alternate Names

Alpha-1,4-N-acetylhexosaminyltransferase EXTL2; alpha-1,4-N-acteylhexosaminyltransferase; Alpha-GalNAcT EXTL2; EC 2.4.1.223; exostoses (multiple)-like 2; Exostosin like 2; Exostosin-like 2; EXTL2; EXTR2; EXT-related protein 2; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; processed exostosin-like 2