Mouse Fc gamma RIIB/CD32b Alexa Fluor® 532-conjugated Antibody

Catalog #: FAB14601X Datasheet / COA / SDS

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FAB14601X-100UG

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Mouse Fc gamma RIIB/CD32b Alexa Fluor® 532-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse Fc gamma RIIB in direct ELISAs. In direct ELISAs, this antibody shows 100% cross-reactivity with recombinant mouse (rm) Fc gamma RIII. In ELISAs, this antibody shows approximately 7% cross-reactivity with rmFc gamma RIII.

Source

Monoclonal Rat IgG2a Clone # 190907

Purification

Protein A or G purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse FcÎ³ RIIB
aa 40-217
Accession # P08101

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 532 (Excitation= 534 nm, Emission= 553 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Fc gamma RIIB/CD32b

Fc gamma RIIB, also known as CD32b, is a low affinity inhibitory receptor for the Fc portion of the IgG molecules. Fc gamma RIIB is expressed on B cells, macrophages, neutrophils, and mast cells and is involved in phagocytosis of immune complexes and modulation of antibody production by B cells.

Long Name

Fc gamma Receptor II

Entrez Gene IDs

2213 (Human); 14130 (Mouse); 289211 (Rat); 102139530 (Cynomolgus Monkey)

Alternate Names

CD32 antigen; CD32b; CD32Fc fragment of IgG, low affinity II, receptor for (CD32); CDw32; Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc gamma RIIB; FCG2; Fc-gamma RII-b; fc-gamma-RIIb; FCGR2; FCGR2B; FcgRIIB; FCRIIB; fcRII-b; IGFR2; IgG Fc receptor II-b; low affinity immunoglobulin gamma Fc region receptor II-b