IL-17/IL-17A is a homodimeric cytokine that is secreted by IL-23 activated Th17 and Tc17 cells. It is upregulated during inflammation and contributes to disease severity by enhancing neutrophil infiltration and the production of pro-inflammatory chemokines. IL-17A can additionally form bioactive heterodimers with IL-17F. IL-17A and the IL-17A/F heterodimer signal through widely expressed receptor complexes containing IL-17 RA and IL-17 RC.
Mouse IL-17/IL-17A (NP_034682.1) VersaClone cDNA
R&D Systems | Catalog # RDC3331
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Background: IL-17/IL-17A
Long Name
Interleukin 17
Alternate Names
CTLA-8, CTLA8, IL-17A, IL17, IL17A
Entrez Gene IDs
Gene Symbol
IL17A
UniProt
Additional IL-17/IL-17A Products
Product Documents for Mouse IL-17/IL-17A (NP_034682.1) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Mouse IL-17/IL-17A (NP_034682.1) VersaClone cDNA
For research use only
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Associated Pathways
