Mouse IL1RAPL2 Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB3068V Datasheet / COA / SDS

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FAB3068V-100UG

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Mouse IL1RAPL2 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse IL1RAPL2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 25% cross‑reactivity with recombinant human (rh) IL1RAPL2 is observed and no cross-reactivity with recombinant mouse (rm) IL-1 R1,

Source

Monoclonal Rat IgG2a Clone # 320017

Purification

Protein A or G purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse IL1RAPL2
Asn18-Ala358
Accession # Q9ERS6

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: IL1RAPL2

Interleukin 1 receptor accessory protein-like 2 (IL1RAPL2), also known as TIGIRR-1 and IL-1 R9, is a member of the IL-1 RI-like family of the IL-1 R/Toll-like receptor superfamily. IL1RAPL2 is a type I transmembrane protein that contains three Ig-like domains in its extracellular region and one intracellular TIR domain. IL1RAPL2 is expressed in the central nervous system, and its deletion is associated with some forms of X-linked mental retardation. An alternately spliced variant lacks the transmembrane and cytoplasmic regions. Within their extracellular domains, mouse IL1RAPL2 shares 99% amino acid sequence identity with human IL1RAPL2.

Long Name

Interleukin 1 Receptor Accessory Protein-like 2

Entrez Gene IDs

26280 (Human); 60367 (Mouse)

Alternate Names

IL-1R10; IL-1R-9; IL1R9IL-1 receptor accessory protein-like 2; IL-1R9IL-1RAPL-2; IL1RAPL2; IL-1RAPL2; IL-1-RAPL-2; IL1RAPL-2IL1RAPL-2-related protein; interleukin 1 receptor 9; interleukin 1 receptor accessory protein-like 2; Three immunoglobulin domain-containing IL-1 receptor-related 1; TIGIRR-1; TIGIRR-1Interleukin-1 receptor 9; X-linked interleukin-1 receptor accessory protein-like 2