Mouse OCIL/CLEC2d Alexa Fluor® 405-conjugated Antibody

Catalog #: AF3376V Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF3376V-100UG

Save 15% on Select RUO Reagents. See Details.

All OCIL/CLEC2d Antibodies

Product Details

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse OCIL/CLEC2d Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse OCIL/CLEC2d in direct ELISAs and Western blots. In Western blots, approximately 35% cross-reactivity with recombinant mouse OCILRP2 is observed and less than 2% cross-reactivity with recombinant human OCIL is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant mouse OCIL/CLEC2d
Ala65-Ser207
Accession # Q91V08

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: OCIL/CLEC2d

Mouse OCIL, also known as C-type lectin-related b (Clrb), is a type II transmembrane protein belonging to the natural killer (NK) cell receptor group of the C-type lectin superfamily. It is found on hematopoietic cells, osteoclasts and chondrocytes. OCIL preferentially binds high molecular weight, sulfated glycosaminoglycans and is a ligand for the mouse NK R-PIB/D receptor. OCIL blocks osteoclast differentiation. Engagement of OCIL with NK R-PIB/D on NK cells inhibits NK cell functions. The extracellular domain of mouse OCIL shares 49% and 71% amino acid sequence identity with rat and human OCIL, respectively.

Long Name

Osteoclast Inhibitory Lectin

Entrez Gene IDs

29121 (Human); 93694 (Mouse)

Alternate Names

CLAXLLT-1; CLEC2D; C-type lectin domain family 2 member D; C-type lectin domain family 2, member D; C-type lectin related f; Lectin-like NK cell receptor; Lectin-like transcript 1; LLT1; LLT1Osteoclast inhibitory lectin; OCIL; OCILmember D