Mouse TFPI-2 Alexa Fluor® 750-conjugated Antibody

Catalog #: AF4045S Datasheet / COA / SDS

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AF4045S-100UG

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All TFPI-2 Antibodies

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Mouse TFPI-2 Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse TFPI-2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5% cross‑reactivity with recombiannt human (rh) TFPI-2, rhTFPI-1, and recombinant mouse TFPI-1 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse TFPI-2
Leu23-Lys211
Accession # O35536

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: TFPI-2

TFPI-2 (tissue factor pathway inhibitor-2; also placental protein 5/PP5) is a secreted, presumably 27‑34 kDa glycoprotein member of the Kunitz domain-containing proteinase inhibitor family. In mouse, it is principally produced by endothelium, hepatocytes and synctiotrophoblasts, and serves as an inhibitor of multiple serine proteinases. Mature mouse TFPI-2 is 208 amino acids (aa) in length. It contains three Kunitz inhibitor domains, the most N-terminal of which (aa 36‑86) is crucial to inhibitor activity. Over aa 23‑211, mouse TFPI-2 shares 86% and 58% aa sequence identity with rat and human TFPI-2, respectively.

Long Name

Tissue Factor Pathway Inhibitor 2

Entrez Gene IDs

7980 (Human)

Alternate Names

Placental protein 5; PP5; PP5FLJ21164; REF-1; TFPI2; TFPI-2; TFPI-2REF1; tissue factor pathway inhibitor 2