Mouse Tryptase beta-1/MCP-7/Mcpt7 Alexa Fluor® 350-conjugated Antibody

Catalog #: FAB1937U Datasheet / COA / SDS

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FAB1937U-100UG

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Mouse Tryptase beta-1/MCP-7/Mcpt7 Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse Tryptase beta ‑1/MCP‑7/Mcpt7 in direct ELISAs and Western blots. In direct ELISAs, 100% cross‑reactivity with recombinant human (rh) Tryptase alpha and rhTryptase beta ‑2 is observed and no cross-reactivity with recombinant mouse MCPT-1 is ob

Source

Monoclonal Rat IgG2a Clone # 263019

Purification

Protein A or G purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Tryptase Î²â€‘1/MCPâ€‘7/Mcpt7
Ile29-Phe273
Accession # Q02844

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Tryptase beta-1/MCP-7

Tryptase beta -1 is a serine protease with trypsin-like activity, which is sometimes also referred to as Mast Cell Protease 7 (MCP-7 or Mcpt7) (1). It is stored in the secretory granules of mouse mast cells (2). It exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of the diverse array of protease inhibitors in plasma (3). The deduced amino acid (aa) sequence for mouse Tryptase beta -1 consists of a signal peptide (aa 1‑18), a pro region (aa 19‑28) and the mature chain (aa 29‑273).

Long Name

Mast Cell Protease 7

Entrez Gene IDs

100503895 (Mouse)

Alternate Names

Mast Cell Tryptase; Mcp7; MCP-7; Mcpt7; TPSB1; TRYB1; Tryptase beta1; Tryptase beta-1