MQAE
Tocris Bioscience | Catalog # 7856
Key Product Details
Description
Wavelength
Product Description
MQAE is a membrane-permeable intracellular chloride ion (Cl-) indicator. The fluorescence intensity of MQAE decreases proportionally as Cl- ions increase. Excitation/emission maxima (λ) are 355 nm and 460 nm respectively. Can be used in fluorescence microscopy and flow cytometry, suitable for use in vivo and in vitro.Optical Data
| λabs | 355 nm |
| λem | 460 nm |
| Extinction Coefficient (ε) | 4850 M-1cm-1 |
| Cell Permeable | Yes |
| pH Sensitivity | Insensitive |
| Application | Confocal imaging, Flow cytometry |
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Product Specifications for MQAE
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 3.26 | 10 | |
| DMSO | 3.26 | 10 |
Preparing Stock Solutions for MQAE
The following data is based on the product molecular weight 326.19.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.66 mL | 153.28 mL | 306.57 mL |
| 0.5 mM | 6.13 mL | 30.66 mL | 61.31 mL |
| 1 mM | 3.07 mL | 15.33 mL | 30.66 mL |
| 5 mM | 0.61 mL | 3.07 mL | 6.13 mL |
Calculators
Background References
References are publications that support the biological activity of the product.
- Wan An ATP-regulated ion transport nanosystem for homeostatic perturbation therapy and sensitizing photodynamic therapy by autophagy inhibition of tumors. ACS Cent.Sci. 2019 PMID: 30834321
- Verkman Synthesis and characterization of improved chloride-sensitive fluorescent indicators for biological applications. Anal.Biochem. 1989 PMID: 2751097
Product Documents for MQAE
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for MQAE
For research use only
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