Product Description
Specific inhibitor of cyclic GMP phosphodiesterase, selective for PDE5 (IC50 = 0.5 μM).
Product Specifications for MY-5445
Molecular Weight
Formula
Storage
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 50 | ||
| Ethanol | 5 |
Preparing Stock Solutions for MY-5445
The following data is based on the product molecular weight 331.80.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 6.03 mL | 30.14 mL | 60.28 mL |
| 2.5 mM | 1.21 mL | 6.03 mL | 12.06 mL |
| 5 mM | 0.60 mL | 3.01 mL | 6.03 mL |
| 25 mM | 0.12 mL | 0.60 mL | 1.21 mL |
Calculators
Background References
References are publications that support the biological activity of the product.
- Hagiwara Effect of 1-(3-chloroanilino)-4-phenylphthalazine (MY-5445), a specific inhibitor of cyclic GMP phosphodiesterase, on human platelet aggregation. J.Pharmacol.Exp.Ther. 1984 PMID: 6141286
- Hidaka and Endo Selective inhibitors of three forms of cyclic nucleotide phosphodiesterase, basic and potential clinical applications. Adv.Cyclic Nucleotide Protein Phosphorylation Res. 1984 PMID: 6144253
Product Documents for MY-5445
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for MY-5445
For research use only
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