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N-(4-Hydroxyphenylacetyl)spermine

Catalog #: 0290 Datasheet / COA / SDS

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0290 has been discontinued.
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N-(4-Hydroxyphenylacetyl)spermine | CAS No. 130210-32-1 | NMDA Receptor Antagonists
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Description: Wasp toxin analog

Chemical Name: N-(N-(4-Hydroxyphenylacetyl)-3-aminopropyl)-(N'-3-aminopropyl)-1,4-butanediamine

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Biological Activity

N-(4-Hydroxyphenylacetyl)spermine is a wasp toxin analog. More potent than PhTX-343 at locust NMJ. Reported to be selective for NMDA receptors in mammalian CNS.

Technical Data

M.Wt:
336.48
Formula:
C18H32N4O2
Solubility:
Soluble in water
Storage:
Desiccate at -20°C
CAS No:
130210-32-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Mono-acylated spermines: antagonists of glutamate receptors.
    Smith et al.
    Eur.J.Pharmacol., 1990;183:472
  2. Invertebrate pharmacological assay of novel, potent glutamate antagonists: acylated spermines.
    Bycroft et al.
    Eur.J.Pharmacol., 1990;183:470

Product Datasheets

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
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