N-Desmethylclozapine

Tocris Bioscience | Catalog # 1007

5-HT2C antagonist
Tocris Bioscience
Discontinued Product
1007 has been discontinued. View all 5-HT2C Receptor Antagonists products.

Key Product Details

Description

5-HT2C antagonist

Alternative Names

Normethylclozapine,Norclozapine
View all 5-HT2C Receptor Antagonists »

Product Description

N-Desmethylclozapine is an a major metabolite of clozapine; a potent and selective 5-HT2C serotonin receptor antagonist.

Product Specifications for N-Desmethylclozapine

Molecular Weight

312.80

Formula

C17H17ClN4

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

8-Chloro-11-(1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine

CAS Number

6104-71-8

PubChem ID

210172

InChI Key

NIBOMXUDFLRHRV-UHFFFAOYSA-N

SMILES

ClC1=CC=C2NC3=C(C=CC=C3)C(=NC2=C1)N1CCNCC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 31.28 100
Ethanol 31.28 100

Preparing Stock Solutions for N-Desmethylclozapine

The following data is based on the product molecular weight 312.80.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.20 mL 15.98 mL 31.97 mL
5 mM 0.64 mL 3.20 mL 6.39 mL
10 mM 0.32 mL 1.60 mL 3.20 mL
50 mM 0.06 mL 0.32 mL 0.64 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 46 publications citing the usage of this product.

Product Documents for N-Desmethylclozapine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for N-Desmethylclozapine

For research use only

Citations for N-Desmethylclozapine

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