N20C hydrochloride

Key Product Details

Product Description

Selective, non-competitive NMDA receptor antagonist (IC₅₀ = 5 μM); binds to the receptor-associated ion channel and prevents glutamate-induced Ca²⁺ influx. Displays neuroprotective activity in vivo. Brain-penetrant.

Product Specifications for N20C hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for N20C hydrochloride

The following data is based on the product molecular weight 304.82.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.28 mL	16.40 mL	32.81 mL
5 mM	0.66 mL	3.28 mL	6.56 mL
10 mM	0.33 mL	1.64 mL	3.28 mL
50 mM	0.07 mL	0.33 mL	0.66 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 22 publications citing the usage of this product.

• Planells-Cases A novel N-MthD.-aspartate receptor open channel blocker with in vivo neuroprotectant activity. J.Pharmacol.Exp.Ther. 2002 PMID: 12065713

Product Documents for N20C hydrochloride