NIKi

Tocris Bioscience | Catalog # 7136

Potent NIK inhibitor
Tocris Bioscience
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Key Product Details

Description

Potent NIK inhibitor

Product Description

NIKi is a potent inhibitor of NF-κB-inducing kinase (NIK) activity (IC50 = 20 nM).

Product Specifications for NIKi

Molecular Weight

366.42

Formula

C20H22N4O3

Storage

Store at -20°C

Purity

≥98%

Chemical Name

4-[3-[2-Amino-5-(2-methoxyethoxy)-4-pyrimidinyl]-1H-indol-5-yl]-2-methyl-3-butyn-2-ol

CAS Number

1202763-91-4

PubChem ID

58221375

InChI Key

ZZIZLABGKZWVAW-UHFFFAOYSA-N

SMILES

COCCOC1=CN=C(N=C1C2=CNC3=CC=C(C#CC(C)(O)C)C=C23)N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 36.64 100

Preparing Stock Solutions for NIKi

The following data is based on the product molecular weight 366.42.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.73 mL 13.65 mL 27.29 mL
5 mM 0.55 mL 2.73 mL 5.46 mL
10 mM 0.27 mL 1.36 mL 2.73 mL
50 mM 0.05 mL 0.27 mL 0.55 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for NIKi

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for NIKi

For research use only

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