NK 252

Tocris Bioscience | Catalog # 5293

Nrf2 activator
Tocris Bioscience

Key Product Details

Description

Nrf2 activator
View all Nrf2 Activators »

Product Description

NK 252 is an Nrf2 activator; interacts with the Nrf2-binding site of Keap1. Downregulates the expression of fibrogenic genes and increases antioxidant effects in NASH rat models of liver disease.

Product Specifications for NK 252

Molecular Weight

285.26

Formula

C13H11N5O3

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N'-(2-pyridinylmethyl)urea

CAS Number

1414963-82-8

PubChem ID

71618700

InChI Key

FNSCFQXZZNCDAI-UHFFFAOYSA-N

SMILES

O=C(NC2=NN=C(C3=CC=CO3)O2)NCC1=CC=CC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
1eq. HCl 28.53 100
DMSO 28.53 100

Preparing Stock Solutions for NK 252

The following data is based on the product molecular weight 285.26.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.51 mL 17.53 mL 35.06 mL
5 mM 0.70 mL 3.51 mL 7.01 mL
10 mM 0.35 mL 1.75 mL 3.51 mL
50 mM 0.07 mL 0.35 mL 0.70 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for NK 252

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for NK 252

For research use only

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