NPE-caged-proton

Tocris Bioscience | Catalog # 3512

Caged proton
Tocris Bioscience

Key Product Details

Description

Caged proton

Alternative Names

NPE-caged-sulfate
View all Caged Compounds »

Product Description

NPE-caged-proton is a 1-(2-nitrophenyl)ethyl caged proton that releases a proton and a sulfate ion upon photolysis at 350 - 355 nm. Generates rapid acidifications (pH jumps) down to pH 2.

Product Specifications for NPE-caged-proton

Molecular Weight

269.21

Formula

C8H8NNaO6S

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

1-(2-Nitrophenyl)ethyl sulfate sodium salt

CAS Number

1186195-63-0

PubChem ID

57369362

InChI Key

LCCXAXUWDTVOHF-UHFFFAOYSA-M

SMILES

[O-][N+](C1=C(C(C)OS([O-])(=O)=O)C=CC=C1)=O.[Na+]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 26.92 100
DMSO 26.92 100

Preparing Stock Solutions for NPE-caged-proton

The following data is based on the product molecular weight 269.21.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.71 mL 18.57 mL 37.15 mL
5 mM 0.74 mL 3.71 mL 7.43 mL
10 mM 0.37 mL 1.86 mL 3.71 mL
50 mM 0.07 mL 0.37 mL 0.74 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.

Product Documents for NPE-caged-proton

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for NPE-caged-proton

For research use only

Citations for NPE-caged-proton

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  • NPE Caged-proton
    Name: Anonymous
    Species: Human
    Verified Customer | Posted 07/17/2020
    When photolyzed Caged-proton is supposed to reduce pH; even strong 365nm UV (~1W/cm^2) for 1 second did not show any change in pH
    Bio-Techne Response
    Thank you for reviewing our product. We are sorry to hear that this antibody did not perform as expected. We have been in touch with the customer to resolve this issue according to our Product Guarantee and to the customer’s satisfaction. We suggested using a shorter wavelength for photolysis and offered a replacement vial, but we did not receive a response.

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