NPEC-caged-dopamine

Tocris Bioscience | Catalog # 3992

Caged dopamine
Tocris Bioscience
Discontinued Product
3992 has been discontinued. View all Non-selective Dopamine Receptor Agonists products.

Key Product Details

Description

Caged dopamine

Product Description

NPEC-caged-dopamine is a NPEC ((N)-1-(2-nitrophenyl)ethyl) caged version of dopamine (Cat. No 3548); releases dopamine leading to D1 receptor activation upon UV light illumination (360 nm). Induces PKA activation and c-Fos expression in cortical and striatal neurons, with striatal neurons demonstrating a significantly greater detection and sensitivity to sub-second dopamine signals as compared to cortical neurons.

Product Specifications for NPEC-caged-dopamine

Molecular Weight

346.33

Formula

C17H18N2O6

Storage

Store at -20°C

Purity

≥99% (HPLC)

Chemical Name

(N)-1-(2-Nitrophenyl)ethylcarboxy-3,4-dihydroxyphenethylamine

CAS Number

1257326-23-0

PubChem ID

90488901

InChI Key

PDNNZLULXSQJGZ-UHFFFAOYSA-N

SMILES

CC(OC(NCCC2=CC=C(O)C(O)=C2)=O)C1=C([N+]([O-])=O)C=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 34.63 100

Preparing Stock Solutions for NPEC-caged-dopamine

The following data is based on the product molecular weight 346.33.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.89 mL 14.44 mL 28.87 mL
5 mM 0.58 mL 2.89 mL 5.77 mL
10 mM 0.29 mL 1.44 mL 2.89 mL
50 mM 0.06 mL 0.29 mL 0.58 mL

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.

Product Documents for NPEC-caged-dopamine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for NPEC-caged-dopamine

For research use only

Citations for NPEC-caged-dopamine

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