NPEC-caged-dopamine
Tocris Bioscience | Catalog # 3992
Product Description
NPEC-caged-dopamine is a NPEC ((N)-1-(2-nitrophenyl)ethyl) caged version of dopamine (Cat. No 3548); releases dopamine leading to D1 receptor activation upon UV light illumination (360 nm). Induces PKA activation and c-Fos expression in cortical and striatal neurons, with striatal neurons demonstrating a significantly greater detection and sensitivity to sub-second dopamine signals as compared to cortical neurons.
Product Specifications for NPEC-caged-dopamine
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 34.63 | 100 |
Preparing Stock Solutions for NPEC-caged-dopamine
The following data is based on the product molecular weight 346.33.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.89 mL | 14.44 mL | 28.87 mL |
| 5 mM | 0.58 mL | 2.89 mL | 5.77 mL |
| 10 mM | 0.29 mL | 1.44 mL | 2.89 mL |
| 50 mM | 0.06 mL | 0.29 mL | 0.58 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.
- Castro Striatal neurones have a specific ability to respond to phasic DA release. J.Physiol. 2013 PMID: 23551948
Product Documents for NPEC-caged-dopamine
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for NPEC-caged-dopamine
For research use only
Citations for NPEC-caged-dopamine
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