NSC 33994

Key Product Details

Product Description

NSC 33994 is a selective inhibitor of JAK2 (IC₅₀ = 60 nM). Displays no effect on Src and TYK2 tyrosine kinase activity at a concentration of 25 μM.

Product Specifications for NSC 33994

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for NSC 33994

The following data is based on the product molecular weight 438.65.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.80 mL	113.99 mL	227.97 mL
0.5 mM	4.56 mL	22.80 mL	45.59 mL
1 mM	2.28 mL	11.40 mL	22.80 mL
5 mM	0.46 mL	2.28 mL	4.56 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.

• Kiss Identification of a novel inhibitor of JAK2 tyrosine kinase by structure-based virtual screening. Bioorg.Med.Chem.Lett. 2009 PMID: 19447617

Product Documents for NSC 33994