NU 9056

Tocris Bioscience | Catalog # 4903

Inhibitor of KAT5 (Tip60)
Tocris Bioscience
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Key Product Details

Description

Inhibitor of KAT5 (Tip60)

Product Description

NU 9056 is a selective KAT5 (Tip60) histone acetyltransferase inhibitor (IC50 values are < 2, 60, 36, and >100 μM for KAT5, p300, pCAF and GCN5, respectively). Inhibits protein acetylation in prostate cancer cell lines and blocks DNA damage response. Decreases proliferation of LNCaP cells; induces apoptosis via caspase activation.

Product Specifications for NU 9056

Molecular Weight

232.37

Formula

C6H4N2S4

Storage

Store at -20°C

Chemical Name

5-(1,2-Thiazol-5-yldisulfanyl)-1,2-thiazole

CAS Number

1450644-28-6

PubChem ID

72201043

InChI Key

MLRAMCAHIWHWRM-UHFFFAOYSA-N

SMILES

C1(SSC2=CC=NS2)=CC=NS1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solubility Soluble in DMSO (supplied pre-dissolved in DMSO, 10mg/ml)

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 36 publications citing the usage of this product.

Product Documents for NU 9056

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for NU 9056

For research use only

Related Research Areas

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  • Efficient NU 9056
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vivo
    Cell Line/Tissue: Retina
    Verified Customer | Posted 07/25/2023
    TESTED THE EFFECT OF NU 9056 ON TREATMENT-INDUCED CELL PROLIFERATION IN MOUSE TISSUE. THE TISSUE SECTIONS WERE STAINED WITH KI67 ANTIBODY IN COMBINATION WITH ANTIBODY FOR CELLS OF INTEREST.
    NU 9056 4903

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