NU 9056
Tocris Bioscience | Catalog # 4903
Inhibitor of KAT5 (Tip60)
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Key Product Details
Description
Inhibitor of KAT5 (Tip60)
Product Description
NU 9056 is a selective KAT5 (Tip60) histone acetyltransferase inhibitor (IC50 values are < 2, 60, 36, and >100 μM for KAT5, p300, pCAF and GCN5, respectively). Inhibits protein acetylation in prostate cancer cell lines and blocks DNA damage response. Decreases proliferation of LNCaP cells; induces apoptosis via caspase activation.
Product Specifications for NU 9056
Molecular Weight
232.37
Formula
C6H4N2S4
Storage
Store at -20°C
Chemical Name
5-(1,2-Thiazol-5-yldisulfanyl)-1,2-thiazole
CAS Number
1450644-28-6
PubChem ID
72201043
InChI Key
MLRAMCAHIWHWRM-UHFFFAOYSA-N
SMILES
C1(SSC2=CC=NS2)=CC=NS1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble in DMSO (supplied pre-dissolved in DMSO, 10mg/ml) |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 36 publications citing the usage of this product.
- Coffey Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer. PLoS One 2012 PMID: 23056207
Product Documents for NU 9056
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for NU 9056
For research use only
Related Research Areas
Citations for NU 9056
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Species: MouseAssay Type: In VivoCell Line/Tissue: RetinaVerified Customer | Posted 07/25/2023TESTED THE EFFECT OF NU 9056 ON TREATMENT-INDUCED CELL PROLIFERATION IN MOUSE TISSUE. THE TISSUE SECTIONS WERE STAINED WITH KI67 ANTIBODY IN COMBINATION WITH ANTIBODY FOR CELLS OF INTEREST.
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