ODQ

Key Product Details

Product Description

ODQ is a potent and selective inhibitor of NO-sensitive guanylyl cyclase.

Product Specifications for ODQ

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for ODQ

The following data is based on the product molecular weight 187.16.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

6 5 4 3 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	5.34 mL	26.72 mL	53.43 mL
5 mM	1.07 mL	5.34 mL	10.69 mL
10 mM	0.53 mL	2.67 mL	5.34 mL
50 mM	0.11 mL	0.53 mL	1.07 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 84 publications citing the usage of this product.

• Hwang Comparison of two soluble guanylyl cyclase inhibitors, methylene blue and ODQ, on sodium nitroprusside-induced relaxation in guinea-pig trachea. Br.J.Pharmacol. 1998 PMID: 9863642
• Fedele In vivo microdialysis study of a specific inhibitor of soluble guanylyl cyclase on the glutamate receptor/nitric oxide/cyclic GMP pathway. Br.J.Pharmacol. 1996 PMID: 8894183
• Garthwaite Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one. Mol.Pharmacol. 1995 PMID: 7544433
• Boulton Nitric oxide-dependent long-term potentiation is blocked by a specific inhibitor of soluble guanylyl cyclase. Neuroscience 1995 PMID: 8596640

Product Documents for ODQ