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Ovalbumin peptide (257-264)
Tocris Bioscience | Catalog # 7790
Immunogenic glycoprotein used as model antigen for immunization and vaccination research.
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Key Product Details
Description
Immunogenic glycoprotein used as model antigen for immunization and vaccination research.
Alternative Names
OVA peptide
Product Description
Ovalbumin peptide (257-264) is an immunogenic glycoprotein used as model antigen for immunization and vaccination research and to investigate antigen presentation and T cell activation. This peptide plays a critical role in cancer studies, serving as a key agent to evaluate macrophage antigen presentation and to drive robust CD8+ T cell proliferation. Used in multiple cancer models, including oral squamous cell carcinoma, breast cancer, glioblastoma, triple-negative breast cancer, esophageal squamous cell carcinoma, and B-cell malignancies. Used for investigation into immune response dynamics, cytotoxic T cell activity, tumor microenvironment interactions, and immune evasion mechanisms.
Product Specifications for Ovalbumin peptide (257-264)
Molecular Weight
963.13
Formula
C45H74N10O13
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
138831-86-4
PubChem ID
447764
InChI Key
JVJGCCBAOOWGEO-RUTPOYCXSA-N
SMILES
O=C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(N)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)N
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Background References
References are publications that support the biological activity of the product.
- Ritter ESCRT-mediated membrane repair protects tumor-derived cells against T cell attack. Science 2022 PMID: 35446649
- Dong Poria cocos polysaccharide induced Th1-type immune responses to ovalbumin in mice. PLOS One 2021 PMID: 33411807
- Jaeger Deciphering the immunopeptidome in vivo reveals new tumour antigens. Nature 2022 PMID: 35705813
- Li Histone demethylase KDM5D upregulation drives sex differences in colon cancer. Nature 2023 PMID: 37344599
- Booty Microfluidic squeezing enables MHC class I antigen presentation by diverse immune cells to elicit CD8+ T cell responses with antitumor activity. J.Immunol. 2022 PMID: 35091434
Product Documents for Ovalbumin peptide (257-264)
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Ovalbumin peptide (257-264)
For research use only
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