P1

Key Product Details

Product Description

P1 is a protein disulfide isomerase (PDI) inhibitor (IC₅₀ = 1.7 μM). Inhibits proliferation of numerous cancer cell lines. Cell permeable.

Product Specifications for P1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for P1

The following data is based on the product molecular weight 583.70.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.71 mL	8.57 mL	17.13 mL
5 mM	0.34 mL	1.71 mL	3.43 mL
10 mM	0.17 mL	0.86 mL	1.71 mL
50 mM	0.03 mL	0.17 mL	0.34 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

• Xu Protein disulfide isomerase interacts with tau protein and inhibits its fibrillization. PLoS One 2013 PMID: 24098548
• Ge Small molecule probe suitable for in situ profiling and inhibition of protein disulfide isomerase ACS Chem.Biol. 2013 PMID: 24070012

Product Documents for P1