P3S

Tocris Bioscience | Catalog # 7974

Reagent for modifying RNA at 2'-OH position, for SHAPE-MAP experiments
Tocris Bioscience
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Key Product Details

Description

Reagent for modifying RNA at 2'-OH position, for SHAPE-MAP experiments

Product Description

P3S is a pyridine sulfonyl triazole able to modify RNA via RNA 2'-OH sulfonylation. P3S can be used for RNA SHAPE-MaP experiments in cell lines or live bacteria. It is stable in aqueous media (with half-lives of several hours) even at room temperature.

Product Specifications for P3S

Molecular Weight

210.21

Formula

C7H6N4O2S

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

3-((1H-1,2,4-Triazol-1-yl)sulfonyl)pyridine

CAS Number

2988852-68-0

InChI Key

LBQFWDRVXUJAAR-UHFFFAOYSA-N

SMILES

O=S(C1=CC=CN=C1)(N2C=NC=N2)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 21.02 100

Preparing Stock Solutions for P3S

The following data is based on the product molecular weight 210.21.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.76 mL 23.79 mL 47.57 mL
5 mM 0.95 mL 4.76 mL 9.51 mL
10 mM 0.48 mL 2.38 mL 4.76 mL
50 mM 0.10 mL 0.48 mL 0.95 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for P3S

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for P3S

For research use only

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