PACMA 31

Key Product Details

Product Description

PACMA 31 is an irreversible protein disulfide isomerase (PDI) inhibitor; inhibits growth of ovarian cancer cells. Suppresses tumor growth in a mouse xenograph model of human ovarian cancer.

Product Specifications for PACMA 31

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for PACMA 31

The following data is based on the product molecular weight 430.47.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.32 mL	11.62 mL	23.23 mL
5 mM	0.46 mL	2.32 mL	4.65 mL
10 mM	0.23 mL	1.16 mL	2.32 mL
50 mM	0.05 mL	0.23 mL	0.46 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

• Xu Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment. Proc.Natl.Acad.Sci.U.S.A. 2012 PMID: 22988091
• Ge Small molecule probe suitable for in situ profiling and inhibition of protein disulfide isomerase. ACS.Chem.Biol. 2013 PMID: 24070012

Product Documents for PACMA 31