Pam2CSK4

Tocris Bioscience | Catalog # 4637

TLR2/6 agonist; induces TNF-α production
Tocris Bioscience

Key Product Details

Description

TLR2/6 agonist; induces TNF-α production
View all Toll-like Receptor Agonists »

Product Description

Pam2CSK4 is a toll-like receptor 2/6 (TLR2/6) agonist. Induces TNF-α production in human mononuclear cells. Also induces proliferation and activation of mouse splenic B cells.

Product Specifications for Pam2CSK4

Molecular Weight

1271.83

Formula

C65H126N10O12S

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

868247-72-7

PubChem ID

71457280

InChI Key

LJUIOEFZFQRWJG-GHYFRYPYSA-N

SMILES

[H]N[C@@H](CSC[C@@H](COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in 0.25% acetic acid

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 10 publications citing the usage of this product.

Product Documents for Pam2CSK4

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Pam2CSK4

For research use only

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  • Pam2CSK4 induces TNFa production and release
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: Macrophages
    Verified Customer | Posted 12/12/2018
    Raw macrophages were stimulated either with LPS (200 ng/ml) or Pam2CSK4 (50 nM) for 8 h to follow TNFa concentration in cell culture medium using ELISA. Pam2CSK4 induced TNFa production and release in a similar extent as LPS.
    Pam2CSK4 4637

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