PD 168568 dihydrochloride

Key Product Details

Product Description

PD 168568 dihydrochloride is a potent and selective dopamine D₄ receptor antagonist (K_i values are 8.8 and 1842 nM at D₄ and D₂ receptors respectively). Reverses amphetamine-stimulated locomotion in vivo and is orally active.

Product Specifications for PD 168568 dihydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for PD 168568 dihydrochloride

The following data is based on the product molecular weight 422.39.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.37 mL	11.84 mL	23.67 mL
5 mM	0.47 mL	2.37 mL	4.73 mL
10 mM	0.24 mL	1.18 mL	2.37 mL
50 mM	0.05 mL	0.24 mL	0.47 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

• Belliotti Isoindolinone enantiomers having affinity for the DA D₄ receptor. Bioorg.Med.Chem.Lett. 1998 PMID: 9873377

Product Documents for PD 168568 dihydrochloride