PD 334581

Key Product Details

Product Description

PD 334581 is an inhibitor of MEK1. Analog of PD 184352 (Cat. No. 4237).

Product Specifications for PD 334581

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for PD 334581

The following data is based on the product molecular weight 545.30.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.83 mL	9.17 mL	18.34 mL
5 mM	0.37 mL	1.83 mL	3.67 mL
10 mM	0.18 mL	0.92 mL	1.83 mL
50 mM	0.04 mL	0.18 mL	0.37 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

• Ohren Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel competitive kinase inhibition. Nat.Struct.Mol.Biol. 2004 PMID: 15543157
• Zhang Targeting cancer with small molecule kinase inhibitors. Nat.Rev.Cancer 2009 PMID: 19104514

Product Documents for PD 334581